Streets of Rage 2, known as Bare Knuckle II in Japan, is a 1992 side-scrolling beat 'em up video game published by Sega for the Genesis/Mega Drive. A sequel to Streets of Rage (1991), the characters Axel Stone and Blaze Fielding return while the game also introduces two new characters: Max Thunder, and Eddie "Skate" Hunter, the younger brother of Adam Hunter from the first game.

Streets of Rage 2 was developed by an ad hoc team of several companies: Sega, Ancient, Shout! Design Works, MNM Software, and H.I.C. Ancient's Ayano Koshiro was the lead graphic designer and one of the game design planners, while her brother Yuzo Koshiro composed the music. The game was programmed by the same team as the original.

Upon release, Streets of Rage 2 received critical acclaim and topped sales charts for months. The game is commonly regarded as the best entry in the series, the best beat 'em up game for the Sega Genesis, one of the best beat 'em up and Sega Genesis games in general, and is considered one of the greatest video games of all time. The game's soundtrack has also been considered one of the greatest of all time.